XXV Swiss NMR Symposium
16 January 2024


Our Sponsors

The Swiss NMR Symposium is a biennial one-day symposium that brings together researchers from all fields of magnetic resonance in Switzerland. This long-standing meeting brings together the entire academic and industrial magnetic resonance community of Switzerland for a unique opportunity to exchange ideas and progresses.

The upcoming event will take place 16 January 2024 at the Biozentrum in Basel. The program will feature presentations by researchers from various NMR groups. In addition, a poster session will complement the presentations, with time set aside for dialogue and discussions. There will be coffee breaks, lunch, and an evening apero, offering numerous opportunities for interactions with fellow attendees and our sponsors.

Deadline for submission of poster and talks is 31 December 2023.


Confirmed Speakers List of Posters Timetable

Prof. Dr. Roland Riek, ETHZ, NMR versatility from 25 to 1200 MHz

Prof. Dr. Oliver Zerbe, University of Zurich, Protein NMR at UZH

Prof. Dr. Daniel Häussinger, University of Basel, Lanthanoide tags for PCS NMR

Prof. Dr. Magdalena Kowalska, University of Geneva, Recent radiation-detected NMR developments at CERN

Prof. Dr. Matthias Ernst, ETH Zürich, Dynamics in Solid-State NMR: How Fast is Fast?

Prof. Dr. Alexander Barnes, ETH Zürich, Magnets, microwaves, and spheres for pulsed in-cell DNP

Prof. Dr. Peter Vermathen, University & Inselspital Bern, 39K MR-Spectroscopy at 7 T in human subjects. Establishment and first applications.

Prof. Dr. Geoffrey Bodenhausen, Ecole Normale Supérieure Paris, Collective long-lived coherences in aliphatic chains: a new tool for drug screening

Dr. Federico De Biasi, EPFL, group Emsley, Optically enhanced 1H NMR spectroscopy

Dr. Alfred Ross, Hoffmann LaRoche AG, Application of NMR spectroscopy for characterization and identity testing of oligonucleotide drug molecules

Dr. Aitor Moreno, Bruker BioSpin, New broadband homonuclear decoupling NMR experiments in Topspin and Helium recovery solutions for NMR spectrometers

Dr. Luc Patiny, Zakodium, www.nmrium.org: Process NMR spectra directly in your browser

Dr. Marcel Aebli, ETH Zürich, group Kovalenko, Disorder in Cesium Lead Halide Perovskite Nanoparticles by Colloidal 133Cs NMR

Dr. Alvar Gossert, ETH Zürich, The various facets of GPCR activation and deactivation

Dr. Wolfgang Jahnke, Novartis, Bio-NMR in drug discovery at Novartis

Dr. Alexander Yakimov, ETH Zürich, group Copéret, Titanium Surface Sites in Ziegler-Natta Catalysts from 47/49Ti MAS NMR Signatures

Dr. Emily Baadsvik, ETH Zürich, group Prüssmann, Mapping the myelin bilayer with short-T 2 MRI

Dr. Mihajlo Novakovic, ETH Zürich, group Allain, No labels required – Restricted diffusion of biomolecules opens up a window into phase-separated condensates

Alexandra Polyakova, University of Basel, group Hiller, Interaction Mode of the Chaperone Trigger Factor with Client Proteins

Ivana Petrovic, University of Basel, group Grzesiek, Elucidating GPCR-arrestin interactions: from multisite phosphorylation to receptor internalisation

Carla Rodrigues, University of Zurich, group Sigel, Using NMR to Start Untangling the BCL2 RNA G-quadruplex Dynamics


The large poster exhibition will be a central element of the conference. Every interested participant can display a poster. Please submit your poster via the registration website. The list of posters will be announced here.

P1 Layara Abiko, University of Basel, group Grzesiek

Biased agonism in the β1-adrenergic G protein-coupled receptor is governed by conformational selection


P2 Saumya Badoni, LRM/ISIC/EPFL, group Emsley

Optimal sensitivity for relayed DNP at fast MAS


P3 Leonie Bourgeois, University of Basel, group Häussinger

Design and Application of LCTs for PCS NMR spectroscopy on RNA


P4 Matthias Bütikofer, ETH Zürich, group Riek

From screening to structure – Boosting NMR-based drug discovery with hyperpolarization and label-free structure determination


P5 Fabio Casagrande, F. Hoffmann-La Roche Ltd, group Biophysics, Lead Discovery

NMR at Roche Basel from small to large Molecules, from liquids to solids, from high to low fields


P6 Dib Chakif, University of Bern, group Furrer

Broadband APT (BAPT): a Versatile APT Experiment with Improved J. Compensation and Optimal Suppression of Artifacts in Cq-only Spectra


P7 Ray Cowen, EPFL, group Emsley

NMR Investigations of Pre-Nucleation Species in Early-Stage Calcium-Silicate-Hydrate Reaction


P8 Lidiia Dubenska, ETH Zürich, group Kovalenko

The 133Cs NMR as a Physical Structure Probe of Lead Halide Perovskites


P9 Agnes Eck, ETH Zürich, group Barnes

Lipid raft targeted DNP


P10 Cesar Fernandez, Novartis Biomedical Research, group Novartis

From weak to strong: an interplay between NMR, in-silico approaches and 3D structures in drug discovery


P11 Chukun Gao, ETH Zürich, group Barnes

Handheld 47 Tesla magnet


P12 Katharina Gaus, Syngenta Crop Protection AG, Stein, group Renold

Quantification at very low limits – mapping applications by spraying robots


P13 Julien Grimont, Idorsia,

NMR @ Idorsia – Overview of a unique swiss army knife in drug discovery


P14 Ummugulsum Gunes, EPFL, group Emsley

Atomic-level Structure Determination of Two-Dimensional Mixed Halide Perovskites by NMR Crystallography


P15 Annika Jagels, LifeMine Therapeutics, group Verdine

Mining the Medicines of Life: Isolation and Structure Elucidation of Fungal Natural Products


P16 Soumyadip Jana, University of Zürich, group Sigel

Structural and Dynamic Insights of the Minimal HDV-Like Ribozyme Drz-Mtgn-1


P17 Thomas Kauf, Solvias AG, group BU Large Molecule / ATMP Services

Application of NMR in Pharmaceutical Industry


P18 Olivier Kirchhoffer, University of Geneva, group Wolfender

Isolation and Structural Elucidation of Anti-Infective Hits from a Large Library of Plant Extracts


P19 Lukas Lätsch, ETH Zürich, group Copéret

NMR Signatures and Electronic Structure of Ti Sites in Titanosilicalite-1 from Solid-State 47/49Ti NMR Spectroscopy


P20 Anna Leder, University of Basel, group Hiller

PDIA6 condensates regulate ER stress signaling


P21 Arnelle Löbbert, ETH Zürich, group Gossert

Switching off a GPCR: receptor desensitization studied at atomic resolution by NMR spectroscopy


P22 Nils Lorz, ETH Zürich, group Gossert

Towards New Drug Screening Approaches With and Without DNP


P23 Lea Marti, ETH Zürich, group Barnes

Spinning in Optical Traps: Towards Optical Magic Angle Spinning Magnetic Resonance


P24 Guillaume Mas, University of Basel, group Hiller

Mapping of the RAS oncogenic activation landscape


P25 Annika Matt, University of Basel, group Häussinger

New lanthanoid chelating tags with novel scaffolds for PCS NMR spectroscopy


P26 Christoph Meyer, Departments of Clinical Research and Radiology, University of Bern, Switzerland, group Vermathen

Complex I, V and MDH2 deficient human skin fibroblasts reveal distinct metabolic signatures by 1H HR-MAS NMR


P27 Marthe Millen, ETH Zürich, group Barnes

Control of Microwave characteristics of a 198 GHz Gyrotron for Magnetic Resonance


P28 Jessie Mosso, CIBM, EPFL, group Cudalbu

Sex- and brain region-specific 1H MRS neurometabolic profiles in young rats with hepatic encephalopathy


P29 Simone Poli, MRM, University of Bern, group Kreis

Tri-Nuclear MRS: Spatial dependence of hepatic glucose uptake dynamics after oral ingestion of deuterated glucose.


P30 Lauren Price, ETH Zürich, group Barnes

Advances in Spherical Rotor DNP


P31 Yu Rao, EPFL, group Emsley

Steady-state Hyperpolarization of 1H in Liquids by Overhauser Dynamic Nuclear Polarization with 13C–1H Polarization Transfer


P32 Pascal Rieder, University of Basel, group Häussinger

Nanobody GPS by PCS: An Efficient NMR Analysis Method for G Protein Coupled Receptors and Other Large Proteins


P33 Marco Ruckstuhl, ETH Zürich, group Gossert

Insights into functional interactions of a GPCR, enabled by isotope labelling in mammalian cells


P34 Simon Rüdisser, ETH Zürich, group Gossert

Conformations of Macrocyclic Peptides Sampled by NMR: Models for Cell-Permeability


P35 Sebastian Sabisch, ETH Zürich, group Kovalenko

Probing the Electronic Structure of Lead Halide Perovskites using 207Pb NMR


P36 Emine Sager, Novartis, group Novartis NMR

Automated Structure Verification in NMR – a forward looking technology using the data of the past


P37 Edward Saliba, ETH Zürich, group Barnes

Adiabatic Solid Effect Simulations for DNP at 790 GHz


P38 Jasmin Schoenzart, Colorado School of Mines/PhoenixNMR, group Barnes/Gennett

High-Resolution NMR Spinning Modules


P39 Amy Sparks, CERN, group Kowalska

Investigating ionic interfacial diffusion in all-solid-state battery materials using ⁸Li β-NMR


P40 Schütz Stefan, Novartis, group Jahnke

Intrinsically disordered regions in the transcription factor MYC:MAX modulate DNA binding via intramolecular interactions


P41 Marta Stefanska, University of Basel, group Hiller

Shedding Light on Indole Derivatives: Studies of PhotoCIDNP NMR Spectroscopy


P42 Mark Tanchev, EPFL, group NMR Platform

Hack, Drill and Spin Wood for Solid-State NMR – an Apprenticeship at the NMR Platform of EPFL


P43 Daria Torodii, EPFL, group Emsley

Barriers to Proton Resolution in Solids


P44 Ran Wei, EPFL, group Emsley

Rational Design of Dinitroxide Polarizing Agents for Dynamic Nuclear Polarization to Enhance Overall NMR Sensitivity


P45 Guodong Weng, University of Bern, group Slotboom

Simultaneous Multi-Region Detection of GABA+ and Glx using 3D Spatially Resolved SLOW-editing and EPSI-readout at 7T 


P46 Gabriela Stadler, ETH Zürich, group Riek

Fragment Screening and Fast Micromolar Detection on a Benchtop NMR Spectrometer Boosted by Photoinduced Hyperpolarization


P47 Gyula Pálfy, ETH Zürich, group Allain

Liquid-liquid phase separation of human hnRNPC1 protein in free and RNA-bound form studied by NMR spectroscopy


P48 Michael Pesek, CERN, group Kowalska

Radiation detected ZULF NMR spectroscopy 


09:00 – 09:40 Welcome Coffee / Registration
09:40 – 09:45 Opening Remarks (Sebastian Hiller)

Session 1 (09:45 – 11:00) Chair: Sebastian Hiller
Prof. Dr. Roland Riek, ETH Zürich, NMR versatility from 25 to 1200 MHz

Carla Rodrigues, University of Zurich, group Sigel, Using NMR to Start Untangling the BCL2 RNA G-quadruplex Dynamics

Dr. Mihajlo Novakovic, ETH Zürich, group Allain, No labels required – Restricted diffusion of biomolecules opens up a window into phase-separated condensates

Dr. Alfred Ross, Hoffmann LaRoche AG, Application of NMR spectroscopy for characterization and identity testing of oligonucleotide drug molecules

Dr. Wolfgang Jahnke, Novartis, Bio-NMR in drug discovery at Novartis

Prof. Dr. Geoffrey Bodenhausen, Ecole Normale Supérieure Paris, Collective long-lived coherences in aliphatic chains: a new tool for drug screening

11:00 – 11:30 Coffee Break

Session 2 (11:30 – 12:35) Chair: Stephan Grzesiek
Prof. Dr. Matthias Ernst, ETH Zürich, Dynamics in Solid-State NMR: How Fast is Fast?

Dr. Luc Patiny, Zakodium, www.nmrium.org: Process NMR spectra directly in your browser

Dr. Federico De Biasi, EPFL, group Emsley, Optically enhanced 1H NMR spectroscopy

Prof. Dr. Alexander Barnes, ETH Zürich, Magnets, microwaves, and spheres for pulsed in-cell DNP

Dr. Aitor Moreno, Bruker BioSpin, New broadband homonuclear decoupling NMR experiments in Topspin and Helium recovery solutions for NMR spectrometers

12:35 – 14:30 Lunch break, poster session, 13:45 – 14:30 Site visit of Basel NMR Facility with Bruker’s Helium recovery system (direct elevator to floor -3)

Session 3 (14:30 -15:30) Chair: Daniel Häussinger
Prof. Dr. Magdalena Kowalska, University of Geneva, Recent radiation-detected NMR developments at CERN

Prof. Dr. Peter Vermathen, University & Inselspital Bern, 39K MR-Spectroscopy at 7 T in human subjects. Establishment and first applications.

 Dr. Emily Baadsvik, ETH Zürich, group Prüssmann, Mapping the myelin bilayer with short-T 2 MRI

Dr. Marcel Aebli, ETH Zürich, group Kovalenko, Disorder in Cesium Lead Halide Perovskite Nanoparticles by Colloidal 133Cs NMR

Dr. Alexander Yakimov, ETH Zürich, group Copéret, Titanium Surface Sites in Ziegler-Natta Catalysts from 47/49Ti MAS NMR Signatures

15:30 – 16:00 Coffee Break

Session 4 (16:00 – 17:00) Chair: Wolfgang Jahnke
Prof. Dr. Oliver Zerbe, University of Zurich, Protein NMR at UZH

Ivana Petrovic, University of Basel, group Grzesiek, Elucidating GPCR-arrestin interactions: from multisite phosphorylation to receptor internalisation

Dr. Alvar Gossert, ETH Zürich, The various facets of GPCR activation and deactivation

Alexandra Polyakova, University of Basel, group Hiller, Interaction Mode of the Chaperone Trigger Factor with Client Proteins

Prof. Dr. Daniel Häussinger, University of Basel, Lanthanoide tags for PCS NMR

17:00 – 17:05 Closing Remarks (Daniel Häussinger)
17:05 – 17:10 Announcing NMR Symposium 2026 in Lausanne: Ran Wei
17:10 – Apero

Program subject to changes.

Biozentrum

Biozentrum, University of Basel
Spitalstrasse 41
CH – 4056 Basel
Switzerland

Location